Related Experiment Videos
Evaluation of commercially available antacid tablets
1Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Tropical Gastroenterology : Official Journal of the Digestive Diseases Foundation
|October 1, 1993
Summary
This study evaluated 23 antacid brands, assessing their cost, dispersion, pH, and neutralizing capacity. Results guide consumers toward potent, fast-acting, and economical antacid choices for acid peptic disease.
Area of Science:
- Pharmacology
- Gastroenterology
Background:
- Antacids are widely used for managing acid peptic diseases.
- A comparative analysis of commercially available antacid brands is necessary to determine optimal therapeutic options.
Purpose of the Study:
- To evaluate the relative efficacy and cost-effectiveness of 23 different antacid tablet preparations.
- To provide a guide for selecting superior antacid formulations based on key performance metrics.
Main Methods:
- Assessment of antacid tablets included composition, cost, dispersion time, pH, and neutralization capacity.
- Neutralization time and cost-effectiveness (cost:neutralizing ratio) were calculated.
- A scoring system was devised to rank antacid preparations.
Main Results:
- Tablet costs varied significantly (Rs 0.13–1.48).
- Dispersion times ranged from 20–90 minutes, with pH from 5.7–9.5.
- Neutralizing capacity spanned 8–169 meq/tablet, with neutralization times of 20–45 minutes.
Conclusions:
- Significant variations exist in the performance and cost of commercial antacids.
- The developed scoring system aids in identifying antacids that are potent, rapid-acting, and economical.
- This research offers valuable insights for healthcare providers and patients in selecting appropriate antacid treatments.