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Antigen presentation by non-classical class I molecules
1Gifford Laboratories for Diabetes Research, University of Texas Southwestern Medical Center, Dallas.
Non-classical class I genes are no longer clearly distinguished from classical ones in mammals, and they are found also in fishes, frogs and chickens. They contribute to immune responses against pathogens. Given the number and diversity of class Ib products, their various tissue distribution patterns, and the wide range of peptides they bind, new functions are to be expected.
Non-classical class I genes are no longer clearly distinguished from classical ones in mammals, and they are found also in fishes, frogs and chickens. They contribute to immune responses against pathogens. Given the number and diversity of class Ib products, their various tissue distribution patterns, and the wide range of peptides they bind, new functions are to be expected.