[Changes of serum lipids during parenteral feeding with a 10 percent of soy oil solution (author's transl)]

The purpose of this investigation was the knowledge of certain events related with the intravenous administration of lipids in patients with parenteral nutrition such as tolerance, clearence and changes in the plasmatic lipid fractions and the effect of heparin as capilar lipoprotein-lipase stimulant and of the insulin as lipogenetic hormone. With intralipid the authors observed elevation of serum total lipid, triglicerids and fatty acids; in this patients the fatty acids went up after addition of heparin because triglicerid elucidation but went down after insulin administration which favor the tisular captation of fatty acids. They do not found alteration in serum cholesterol. The results with heparin and insulin suggest a greater and more rapid clearence of plasmatic lipids probably by incorporation of them to the tissues. This feature minimize the risk of exogen hyperlipemia, hyperosmolarity and metabolic acidosis.