Nutritional disorder of anorexia nervosa: a review

In the treatment of anorexia nervosa, the importance of weight restoration has been well documented. Resting energy expenditure, which is initially reduced, often increases markedly in association with refeeding. Previous studies that have examined micronutrient status in anorexia nervosa have reported inconsistent and sometimes contradictory conclusions, due to the heterogeneity of the population, the cross-sectional nature of these investigations, and, at times, the use of inappropriate methods to determine nutrient status. Abnormal nutritional findings in patients with anorexia nervosa are primarily a consequence of semistarvation. Neuroendocrine abnormalities, degree of recovery, and phase of treatment affect interpretation of data. Despite the importance of nutritional rehabilitation, few controlled studies that address the clinical efficacy of various dietary treatment regimens have been conducted.