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Differences in HLA-DR association with rheumatoid arthritis among migrant Indian communities in South Africa
1Department of Medicine, University of Natal, Durban, South Africa.
British Journal of Rheumatology
|May 1, 1994
Abstract:
Previous surveys among Indians with RA have shown a significant association with HLA DR4 in North India and with HLA DR1 in the UK. We studied a migrant Indian population in South Africa to determine their genetic associations with RA. A group of 121 unrelated RA patients from three communities (Hindi, Muslims and Tamils) were studied. The Muslims showed a significant association with DR4 but the Hindi and Tamils showed a significant association with DR10. This survey shows that the Indian community is a heterogenous group regarding their HLA associations with RA and different associations are noted in the various communities.