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Disruption of behavioral recovery by the anti-convulsant phenobarbital
1Department of Psychology, University of Colorado, Boulder 80309.
Brain Research
|January 28, 1994
Abstract:
The effects of the anti-convulsant phenobarbital on recovery of function was assessed. Phenobarbital, which is frequently administered to humans after brain injury, was injected for 7 days beginning 48 h after unilateral cortex lesions in rats. Recovery from somatosensory deficits was significantly delayed in phenobarbital treated animals. These results provide additional evidence that anti-convulsants interfere with recovery when administered after brain damage.