Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Neuropathology required from "brain death"]

F Ikuta1, S Takeda

  • 1Department of Pathology, Niigata University.

Rinsho Shinkeigaku = Clinical Neurology
|December 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of Deep Thermal Rehabilitation System Using Resonant Cavity Applicator During Knee Experiments.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2018
Same author

Restoration of activity for induction of experimental allergic peripheral neuritis by a combination of myelin basic protein P2 and gangliosides from peripheral nerve.

Neuroscience letters·2009
Same author

Intrauterine methylmercury intoxication. Consequence of the inherent brain lesions and cognitive dysfunction in maturity.

Brain research·2000
Same author

Distinct pattern of neuronal degeneration in the fetal rat brain induced by consecutive transplacental administration of methylmercury.

Brain research·2000
Same author

Process of repair in the neuroepithelium of developing rat brain during neurogenesis: chronological and quantitative observation of DNA-replicating cells.

Brain research. Developmental brain research·1998
Same author

Selective involvement of large motor neurons in the spinal cord of rats treated with methylmercury.

Journal of the neurological sciences·1998
Same journal

[Let's present at a regional meeting].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[Editor's Note].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[Notice for Members].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[The Proceedings of the 250th Kyushu Regional Meeting of the Japanese Society of Neurology].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[The Proceedings of the 116th Tohoku Regional Meeting of the Japanese Society of Neurology].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[Metagenomic analysis for central nervous system infections: clinical utility and future directions].

Rinsho shinkeigaku = Clinical neurology·2026
See all related articles

Brain death involves severe increased intracranial pressure and brain stem hemorrhages. Autolysis is prominent, particularly in the brain stem, indicating cessation of blood flow.

Area of Science:

  • Neuropathology
  • Forensic Pathology

Context:

  • Investigated 84 autopsied Japanese patients clinically diagnosed with brain death.
  • Examined pathoanatomical changes post-mortem.

Purpose:

  • To pathoanatomically investigate the brains of individuals declared brain dead.
  • To understand the extent and nature of tissue degradation and blood flow cessation.

Summary:

  • All cases exhibited severe increased intracranial pressure (IICP) with brain stem tegmentum hemorrhages.
  • Brain autolysis was consistently more severe in the brain stem than visceral organs.
  • Cessation of cerebral blood flow in the brain stem was inferred at the time of diagnosis.
  • Spinal cord and hypothalamic neurons, particularly in the supraoptic nucleus, showed prolonged viability post-diagnosis.

Related Experiment Videos

Impact:

  • Provides detailed neuropathological findings in clinically diagnosed brain death.
  • Clarifies the timeline of tissue viability and degradation in the central nervous system post-brain death declaration.
  • Contributes to the understanding of post-mortem changes relevant to forensic and clinical practice.