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Brain-derived neurotrophic factor (BDNF): role in neuronal development and survival
1Department of Anatomy, University Medical Academy, Poznań.
Folia Morphologica
|January 1, 1993
Abstract:
In 1989 Leitbrock et al. reported the full primary structure of brain-derived neurotrophic factor. The messenger RNA for BDNF was found predominantly in the central nervous system, and the sequence of protein indicated its structural relation to NGF. BDNF belongs to a larger family of neurotrophic molecules. It stimulates the neurite outgrowth and supports neuronal survival.