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AIDS-related Kaposi's sarcoma: a review
1Department of Medical Oncology and Hematology, Johannesburg Hospital, Medical School and University of the Witwatersrand, South Africa.
Abstract:
Infection with the human immunodeficiency virus (HIV) is the primary cause of AIDS and related disorders. Infection with HIV results in diminished cellular immunity, propensity to opportunistic infections, and an increased incidence of certain neoplasms. Kaposi's sarcoma (KS) is the most common neoplasm in persons infected with HIV. This epidemic, or HIV-related KS, usually follows an aggressive course with involvement of skin, lymph nodes, and internal organs. Normally, the disease has a progressive clinical course despite being responsive to radio- or chemotherapy.