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Related Experiment Videos

Antifungal agents: an overview. Part I

A K Gupta1, D N Sauder, N H Shear

  • 1Department of Medicine, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.

Journal of the American Academy of Dermatology
|May 1, 1994
PubMed
Summary

Recent advances in treating fungal skin diseases are changing antifungal therapy choices. This review covers traditional treatments and upcoming innovations for better patient outcomes.

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Area of Science:

  • Dermatology
  • Mycology
  • Pharmacology

Background:

  • Cutaneous fungal infections remain a significant clinical challenge.
  • Therapeutic options for superficial mycoses have evolved considerably.
  • Understanding historical treatments is crucial for appreciating modern advancements.

Purpose of the Study:

  • To review traditional therapies for cutaneous fungal diseases.
  • To provide context for recent therapeutic innovations.
  • To inform future antifungal treatment strategies.

Main Methods:

  • Literature review of established antifungal agents.
  • Analysis of historical treatment protocols for fungal infections.
  • Synthesis of information on polyenes, griseofulvin, topical agents, and older azoles.

Main Results:

  • Traditional antifungal therapies include polyenes, griseofulvin, older topical agents, and older azoles.
  • These foundational treatments established the basis for current therapeutic approaches.
  • A comprehensive understanding of these agents is presented.

Conclusions:

  • Traditional therapies, while effective, have limitations.
  • Recent advances are poised to significantly alter antifungal prescribing.
  • Part II of this review will detail these emerging therapies.

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