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Related Concept Videos

Necrosis01:16

Necrosis

6.6K
Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
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Related Experiment Video

Updated: Feb 10, 2026

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants
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A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants

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Thymic necrosis in slaughtered Nile crocodiles

M L Penrith1, F W Huchzermeyer

  • 1Onderstepoort Veterinary Institute, Republic of South Africa.

Journal of the South African Veterinary Association
|September 1, 1993
PubMed
Summary

Necrosis and granulomas in the thymus were observed in apparently healthy, slaughtered crocodiles from South African farms. This suggests thymic necrosis may be common in intensively farmed crocodiles, though the cause is unknown.

Area of Science:

  • Veterinary Pathology
  • Comparative Pathology
  • Crocodilian Health

Background:

  • Intensive farming practices for crocodiles can impact animal health.
  • The thymus is a crucial organ in the immune system of vertebrates.
  • Understanding pathological conditions in farmed animals is essential for disease prevention.

Observation:

  • Microscopic examination of thymus tissue from slaughtered crocodiles revealed foci of necrosis.
  • Heterophilic granulomas were observed within the medullary region of the thymus.
  • These lesions were found in crocodiles from four different South African crocodile farms.

Findings:

  • The study identified thymic necrosis as a potential condition in intensively reared slaughter crocodiles.
  • Preliminary results indicate that this condition may occur commonly in this population.

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  • The exact etiology or cause of the observed thymic necrosis remains undetermined.

    • Implications:

    • Thymic necrosis could be a significant health issue in intensive crocodile farming operations.
    • Further research is needed to identify the causative agent(s) of thymic necrosis.
    • Understanding and addressing this condition may improve the overall health and welfare of farmed crocodiles.