Related Experiment Video

Updated: Aug 18, 2026

Establishment and Characterization of UTI and CAUTI in a Mouse Model
08:40

Establishment and Characterization of UTI and CAUTI in a Mouse Model

Published on: June 23, 2015

Urinary pathogens in the male

R Maskell, L Pead, R J Hallett

    British Journal of Urology
    |December 1, 1975
    PubMed

    Insights

    Urinary tract infections (UTIs) in boys are caused by different pathogens than in girls or adult males. Infection in boys likely originates in the prepuce or urethra, unlike in girls where it stems from the bowel.

    Area of Science:

    • Urology
    • Microbiology
    • Pediatrics

    Background:

    • Urinary tract infections (UTIs) are common in children.
    • The etiology of UTIs in prepubertal boys differs from that in girls and adult males.

    Purpose of the Study:

    • To investigate the distinct pathogens responsible for urinary infections in boys compared to girls and adult males.
    • To explore the potential origin of UTIs in boys, focusing on the prepuce and urethra.

    Main Methods:

    • Comparative analysis of pathogens causing UTIs in boys, girls, and adult males.
    • Examination of prepuce flora in boys with and without a history of UTIs.

    Main Results:

    • Pathogens causing UTIs in boys are significantly different from those in girls and adult males.
    • Infection focus in boys appears to be the preputial sac or urethra, not the bowel.
    • Differences in infecting organisms between boys and adult males may involve prostatic secretions.

    Conclusions:

    • The origin and causative agents of UTIs vary by sex and age group.
    • Preputial and urethral colonization are likely key factors in pediatric male UTIs.
    • Prostatic secretions may play a role in the distinct UTI pathogen profiles observed in adult males.

    More Related Videos

    Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice10:23

    Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice

    Published on: December 1, 2017

    An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection07:57

    An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection

    Published on: June 24, 2025

    Related Concept Videos

    Disorders of the Male Reproductive System01:20

    Disorders of the Male Reproductive System

    Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
    Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
    Nursing Assessment of the Genitourinary System I: Health History01:21

    Nursing Assessment of the Genitourinary System I: Health History

    The genitourinary system is critical to maintaining fluid balance, waste elimination, and reproductive function. Nurses play a vital role in assessing this system, beginning with a thorough health history. This process involves gathering patient information, identifying risk factors, and recognizing symptoms of genitourinary disorders. Early detection is vital for timely interventions and management.1. Gathering Patient InformationA complete health history includes the patient’s personal,...
    Urinary Tract Infection I: Introduction01:26

    Urinary Tract Infection I: Introduction

    Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
    Urinary Tract Infection II: Pathophysiology01:25

    Urinary Tract Infection II: Pathophysiology

    The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
    Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

    Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

    A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
    Microbiota of the Urogenital Tract01:28

    Microbiota of the Urogenital Tract

    The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...