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Updated: Aug 4, 2026

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Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
Published on: April 9, 2019
Summary
Transrectal ultrasound (TRUS) enhances prostate cancer diagnosis and staging accuracy. This imaging technique, when performed by experienced professionals, offers precise evaluation of prostate conditions, including benign prostatic hyperplasia and prostatitis.
Area of Science:
- Urology
- Medical Imaging
- Oncology
Background:
- Transrectal ultrasound (TRUS) utilizes high-frequency probes (approx. 7 MHz) for detailed imaging of prostate zonal anatomy.
- Prostate diseases often cause characteristic changes detectable via ultrasound.
- Early detection and accurate staging of prostate cancer are critical for effective treatment.
Purpose of the Study:
- To evaluate the diagnostic capabilities of transrectal ultrasound (TRUS) in identifying prostate carcinoma and other prostatic diseases.
- To assess the accuracy of TRUS in preoperative staging of prostate cancer.
- To determine the efficacy and safety of TRUS-guided biopsies compared to traditional methods.
Main Methods:
- High-frequency (7 MHz) transrectal ultrasound probes were employed for imaging the prostate.
- TRUS was used to identify hypoechoic lesions characteristic of prostate carcinoma.
- TRUS-guided transrectal biopsies were performed using semi-automatic systems.
Main Results:
- TRUS diagnosed prostate carcinoma more frequently than digital rectal palpation, including ventrally located tumors.
- Preoperative staging accuracy using TRUS surpassed other available methods.
- TRUS-guided biopsies were found to be safe, complication-free, and more accurate than digitally guided biopsies.
- Precise evaluation of adenoma volume and malignancy was achieved.
- Characteristic echogenicity changes allowed for the diagnosis of prostatitis and/or vesiculitis.
Conclusions:
- Transrectal ultrasound (TRUS) is a highly effective tool for diagnosing prostate cancer and assessing its stage.
- TRUS enables accurate differentiation of benign and malignant prostate conditions, including BPH and inflammatory processes.
- The diagnostic reliability of TRUS is significantly dependent on the expertise of the examiner.
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