Related Experiment Videos
Effects of 100% O2 exposure on hypoxic ventilatory response
M F Chowdhury1, A Masuda, W Nakamura
1Department of Physiology, School of Medicine, Chiba University, Japan.
Sleep
|December 1, 1993
Abstract:
Comparison of the slope of progressive isocapnic hypoxia obtained with and without prior O2 exposure (termed + and -O2 runs, respectively) placed our subjects into two groups. Positive responders had a significantly lower slope in -O2 runs compared with similar runs in negative responders, but they also improved hypoxic ventilatory response (HVR) significantly after O2 exposure. Negative responders had a high -O2 slope that did not alter significantly after O2 exposure. We conclude that ambient air hypoxic depression is active in positive responders who are O2 sensitive.