Related Experiment Videos
[Local recurrence after organ saving kidney tumor surgery]
D Brkovic1, G Riedasch, R Waldherr
1Urologische Universitätsklinik und Poliklinik Heidelberg.
Der Urologe. Ausg. A
|March 1, 1994
Summary
Nephron-sparing surgery for renal cell carcinoma in solitary kidneys or bilateral tumors shows a 12% local recurrence rate. This study advises against parenchyma-sparing surgery in elective cases due to recurrence risks.
Area of Science:
- Urology
- Oncology
Context:
- Nephron-sparing surgery (NSS) is debated for elective renal cell carcinoma (RCC) treatment when a normal contralateral kidney exists.
- Local tumor recurrence is a primary concern against NSS in elective scenarios.
Purpose:
- To evaluate the long-term outcomes and local recurrence rates of NSS in patients with renal cell carcinoma (RCC) in solitary kidneys or bilateral tumors.
Summary:
- A retrospective analysis of 107 patients undergoing NSS for RCC in solitary or bilateral kidneys between 1971 and 1989 revealed a 12% local recurrence rate.
- Recurrences occurred between 4 and 112 months post-resection, with a significant proportion within the first two years, suggesting potentially distinct recurrence patterns.
- A correlation between tumor grade and recurrence interval was observed, with lower-grade tumors having longer intervals, sometimes exceeding typical elective follow-up periods.
Impact:
- The findings suggest caution regarding NSS in elective indications, even with favorable survival rates in mandatory cases.
- The study indicates that parenchyma-sparing surgery may not be recommended for elective renal cell carcinoma resections due to the risk of local recurrence.