Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Genetic and immunologic studies after space flight]

H Tuschl1, R Kovac, W Klein

  • 1Osterreichisches Forschungszentrum Seibersdorf Ges.m.b.H., Osterreich.

Wiener Medizinische Wochenschrift (1946)
|January 1, 1993
PubMed
Summary

Spaceflight reduced natural killer cells and impaired lymphocyte activity, altering DNA structure. The Austrian cosmonaut

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Backpropagation algorithms and Reservoir Computing in Recurrent Neural Networks for the forecasting of complex spatiotemporal dynamics.

Neural networks : the official journal of the International Neural Network Society·2020
Same author

Robustness of network measures to link errors.

Physical review. E, Statistical, nonlinear, and soft matter physics·2014
Same author

UDS-test with freon 11 (R-11).

Environmental science and pollution research international·2013
Same author

Risk factors associated with surgical site infections following vascular surgery at a German university hospital.

Epidemiology and infection·2012
Same author

Integration of the e-Learning into the medical university curricula.

Bratislavske lekarske listy·2012
Same author

[Multiresistant pathogens in surgery].

Der Unfallchirurg·2011

Area of Science:

  • Immunology
  • Space Medicine
  • Molecular Biology

Context:

  • Investigated the physiological effects of spaceflight on immune cells.
  • Utilized data from the Austrian cosmonaut during the Austromir mission.

Purpose:

  • To assess the impact of space travel on peripheral blood lymphocytes.
  • To analyze changes in lymphocyte subsets, DNA synthesis, and DNA structure post-flight.

Summary:

  • Spaceflight led to a decrease in natural killer cells and impaired lymphocyte function.
  • Observed slight modifications in DNA structure, including unscheduled DNA synthesis and sister chromatid exchanges.
  • Immune parameters and DNA structure returned to baseline levels within 4 weeks, suggesting effective repair mechanisms.

Related Experiment Videos

Impact:

  • Provides insights into the immunological risks of space missions.
  • Highlights the potential for DNA damage and recovery in astronauts.
  • Informs strategies for astronaut health maintenance during long-duration spaceflight.