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[Bowen's disease. A report of 9 cases]
C de Miguel Sánchez1, O Olmos Carrasco, A Sáez-Berlana
1Consulta de Dermatología, San Sebastián de los Reyes, Hospital La Paz, Madrid.
Objective:
To revise clinical histological, therapeutic and evolutive specifications of Bowen's disease. To emphasise the importance of an early diagnosis and to promote treatment with topical 5-fluorouracil by the family doctor.
Design:
Descriptive and transversal study.
Setting:
Outpatient and dermatology departments in a hospital in the metropolitan area of Madrid.
Patients And Other Participants:
Nine patients (5 male and 4 female), aged over 50, with slightly pigmented skin and diagnosed to have Bowen's disease.
Treatment:
In five patients. Topical 5-fluorouracil (Efudix) was applied once a day for 20-30 days. Surgery was performed on three patients and one underwent radiotherapy.
Measurements And Main Results:
The clinical histories of the patients were used. In each case a histological study of the papule that had confirmed diagnosis was carried out. Treatment was effective in all patients and no recidivation was observed during the one year follow up.
Conclusions:
An early diagnosis and treatment of Bowen's disease is important for preventing its progression to invasive epidermoid carcinoma and later dissemination. The use of topical 5-fluorouracil is an efficient measure that can be prescribed by the family doctor.