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Inflammatory pseudotumor of the liver: appearance on MRI
M E Flisak1, D M Budris, M C Olson
1Department of Radiology, Loyola University Medical Center, Maywood, IL 60153.
Abstract:
Inflammatory pseudotumor of the liver is a rare entity; fewer than 50 cases have been reported in the world literature. Its appearance on both computerized tomography (CT) and ultrasound have been previously described. To our knowledge, this is the first report of its appearance on magnetic resonance imaging (MRI). The lesion demonstrated increased signal intensity on T-1 and T-2 spin-echo and inversion recovery (STIR) sequences in relationship to normal liver. The signal characteristics, however, were nonspecific and diagnosis required biopsy confirmation. There was spontaneous resolution with conservative management, and this was documented on follow-up CT and MRI.
Insights
Inflammatory pseudotumor of the liver is a rare condition. This study details its appearance on magnetic resonance imaging (MRI), showing nonspecific signal characteristics that necessitate biopsy for diagnosis.
Area of Science:
- Hepatology
- Radiology
- Pathology
Background:
- Inflammatory pseudotumor of the liver is an exceptionally rare condition, with limited documented cases globally.
- Previous literature has described its presentation on computed tomography (CT) and ultrasound imaging.
- This report introduces the first documented appearance of hepatic inflammatory pseudotumor on magnetic resonance imaging (MRI).
Observation:
- The liver lesion exhibited increased signal intensity across T-1, T-2 spin-echo, and short tau inversion recovery (STIR) sequences relative to normal liver parenchyma.
- These MRI signal characteristics were found to be nonspecific.
- Diagnosis was confirmed through biopsy.
Findings:
- The observed MRI signal characteristics of hepatic inflammatory pseudotumor are nonspecific.
- Biopsy confirmation is essential for accurate diagnosis.
- The lesion demonstrated spontaneous resolution under conservative management.
Implications:
- This case expands the understanding of hepatic inflammatory pseudotumor imaging findings, particularly on MRI.
- The nonspecific nature of MRI signals highlights the continued importance of histopathological confirmation.
- The potential for spontaneous resolution with conservative management offers a new perspective on treatment approaches for this rare liver entity.