Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

BTPS correction for ceramic flow sensor

J L Hankinson1, J O Viola, E L Petsonk

  • 1Centers for Disease Control, National Institute for Occupational Safety and Health-ALOSH, Morgantown, WVa 26505.

Chest
|May 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The association between tobacco burden and "dirty chest" is unlikely to follow a linear dose-response pattern.

The British journal of radiology·2012
Same author

Workplace spirometry monitoring for respiratory disease prevention: a methods review.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2010
Same author

Changes in the FEV₁/FVC ratio during childhood and adolescence: an intercontinental study.

The European respiratory journal·2010
Same author

Comparison of storage phosphor computed radiography with conventional film-screen radiography in the recognition of pneumoconiosis.

The European respiratory journal·2009
Same author

Age- and size-related reference ranges: a case study of spirometry through childhood and adulthood.

Statistics in medicine·2008
Same author

Using the lower limit of normal for the FEV1/FVC ratio reduces the misclassification of airway obstruction.

Thorax·2008
Same journal

The effect of a two-day stay at high altitude (2500 m) on right ventricular afterload and oxygen delivery in patients with pulmonary vascular disease A randomized controlled crossover trial.

Chest·2026
Same journal

A Comparative Study of Radiation Exposure in Conventional and Robotic Bronchoscopy.

Chest·2026
Same journal

Independent Prognostic Contributions of Anti-Ro52 and Anti-MDA5 in Autoimmune-Associated Interstitial Lung Disease.

Chest·2026
Same journal

Lung aeration and gas exchange in SGA or AGA infants with moderate-severe BPD: secondary analysis of the PATH-BPD study.

Chest·2026
Same journal

Lung Cancer Incidence and Mortality after Negative Low-Dose CT Screening Results.

Chest·2026
Same journal

Symptom prevalence and impact on lung cancer risk in the SUMMIT study.

Chest·2026
See all related articles

Commercial spirometers often use a static correction for body temperature, pressure, and saturation (BTPS). This study shows a dynamic BTPS correction is needed for accurate forced expiratory volume (FEV1) measurements, especially with repeated maneuvers.

Area of Science:

  • Pulmonary Function Testing
  • Biomedical Engineering
  • Respiratory Physiology

Background:

  • Commercially available spirometers commonly employ unheated ceramic elements for airflow sensing.
  • Current spirometry practice often utilizes a static correction factor for body temperature, pressure, and saturation (BTPS) adjustments, typically around 30% of the full correction.

Purpose of the Study:

  • To evaluate the accuracy of the conventional static BTPS correction factor in spirometry.
  • To investigate the need for a dynamic BTPS correction factor for improved FEV1 measurements.
  • To explore the utility of sensor exit air temperature in estimating a dynamic BTPS correction.

Main Methods:

  • Tested spirometer sensors using a mechanical pump with room air and heated, humidified air (37°C).

Related Experiment Videos

  • Employed volume ramps and American Thoracic Society (ATS) standard waveforms for sensor evaluation.
  • Assessed FEV1 variability across repeated maneuvers, varying time intervals and maneuver volumes, using both mechanical and human subject testing over several days.

    • Main Results:

    • The percent difference in FEV1 using room versus heated air ranged from 0.3% to 6.2%, influenced by maneuver history, timing, volume, and sensor temperature.
    • A consistent rise in sensor exit air temperature was observed with successive maneuvers using heated air.
    • Human subject testing revealed a maneuver order effect similar to mechanical pump results, indicating dynamic influences on FEV1 accuracy.

    Conclusions:

    • A dynamic, rather than static, BTPS correction factor is essential for precise forced expiratory volume (FEV1) estimations.
    • Dynamic correction is crucial for minimizing erroneous variability between successive spirometry maneuvers.
    • Utilizing sensor exit air temperature offers a viable method for estimating a dynamic BTPS correction, potentially achieving FEV1 accuracy within +/- 3% for exit temperatures between 5°C and 28°C.