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Acute hypoxemic respiratory failure following intrapleural thrombolytic therapy for hemothorax
M D Frye1, M Jarratt, S A Sahn
1Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston.
Chest
|May 1, 1994
Abstract:
Intrapleural instillation of thrombolytic agents has been useful in the treatment of hemothorax when thoracostomy tube drainage is unsuccessful. We present a patient who developed acute hypoxemic respiratory failure following the intrapleural instillation of both streptokinase and urokinase 24 h apart. Hypoxemia most likely resulted from a direct effect of the products of fibrinolysis on the pulmonary circulation.