Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Allergy and immunology

D L Smith1, R D deShazo

  • 1University of South Alabama, Mobile.

JAMA
|June 1, 1994
PubMed
Summary
This summary is machine-generated.

Fatal asthma cases are rising despite increased medication spending. New biotechnologies offer potential for immune-regulating treatments targeting atopy, a key factor in allergic asthma.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Electromagnetic waves focused by a negative-index planar lens.

Physical review. E, Statistical, nonlinear, and soft matter physics·2003
Same author

Racial differences in bone turnover and calcium metabolism in adolescent females.

The Journal of clinical endocrinology and metabolism·2003
Same author

Telomeric protein distributions and remodeling through the cell cycle in Saccharomyces cerevisiae.

Molecular biology of the cell·2003
Same author

A host-specific bacteria-to-plant signal molecule (Nod factor) enhances germination and early growth of diverse crop plants.

Planta·2003
Same author

Calculations and measurements of wire and/or split-ring negative index media.

Physical review. E, Statistical, nonlinear, and soft matter physics·2002
Same author

The major Nod factor of Bradyrhizobium japonicum promotes early growth of soybean and corn.

Journal of experimental botany·2002
Same journal

WHO Issues Guidelines for Treating Ebola and Marburg Viruses.

JAMA·2026
Same journal

FDA Approves Additional Naloxone Nasal Spray for Opioid Overdose.

JAMA·2026
Same journal

HIV May Hide in More Cells Than Previously Thought-Here's What That Could Mean for a Cure.

JAMA·2026
Same journal

US Dietary Supplement Use Increasing, Especially in Older Adults.

JAMA·2026
Same journal

Heat Stress From Climate Change Surges Globally.

JAMA·2026
Same journal

Strength Training Linked With Lower Cardiovascular Disease Risk in Women.

JAMA·2026
See all related articles

Area of Science:

  • Immunology
  • Allergy Research
  • Biotechnology

Background:

  • A rise in fatal asthma cases has been observed, coinciding with increased spending on asthma medications.
  • Atopy, a genetic predisposition to allergic reactions, is characterized by the production of allergen-specific immunoglobulin E (IgE).

Purpose of the Study:

  • To explore the potential of biotechnology-derived proteins in regulating immune responses for managing severe asthma.
  • To investigate novel therapeutic strategies beyond conventional asthma medications.

Main Methods:

  • Review of current asthma epidemiological data.
  • Analysis of the role of atopy and IgE in severe asthma.
  • Exploration of biotechnological approaches for immune modulation.

Related Experiment Videos

Main Results:

  • Despite increased medication use, fatal asthma remains a concern.
  • Atopy and IgE production are central to the pathophysiology of allergic asthma.
  • Biotechnology enables the development of immune-regulating proteins.

Conclusions:

  • Conventional asthma treatments may be insufficient for severe cases.
  • Targeting atopy and IgE with biotechnological interventions shows promise.
  • Further research into protein-based immunotherapies is warranted for fatal asthma.