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Related Experiment Videos

Haemorrhagic pituitary tumours

C M Lazaro1, W Y Guo, M Sami

  • 1Department of Neuroradiology, Karolinska Sjukhuset, Stockholm, Sweden.

Neuroradiology
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

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Intratumoral hemorrhage was identified in 12 of 69 pituitary tumor patients via MRI. Most hemorrhages occurred in macroadenomas, including prolactinomas and non-functioning adenomas.

Area of Science:

  • Neuroimaging
  • Endocrinology
  • Oncology

Background:

  • Pituitary tumors are common intracranial neoplasms.
  • Intratumoral hemorrhage is a recognized complication of pituitary tumors, potentially leading to pituitary apoplexy.
  • Magnetic resonance imaging (MRI) is crucial for diagnosing pituitary tumors and their complications.

Purpose of the Study:

  • To investigate the prevalence and characteristics of intratumoral hemorrhage in pituitary tumors using MRI.
  • To correlate hemorrhage findings with tumor types and clinical presentation.

Main Methods:

  • Retrospective analysis of 69 patients with pituitary tumors.
  • MRI evaluation for intratumoral hemorrhage, characterized by high signal intensity on short TR/TE sequences.
  • Correlation of imaging findings with tumor histology and clinical data.

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Main Results:

  • 12 out of 69 patients (17.4%) showed evidence of intratumoral hemorrhage on MRI.
  • Hemorrhage predominantly occurred in macroadenomas (10/12).
  • Common tumor types with hemorrhage included prolactinomas (5/12) and non-functioning adenomas (4/12).
  • Two patients presented with clinical symptoms of pituitary apoplexy.
  • No patient required surgery due to hemorrhage size; 5 underwent surgical verification and 6 had follow-up MRI.

Conclusions:

  • Intratumoral hemorrhage is a significant finding in a subset of pituitary tumors, particularly macroadenomas.
  • MRI is effective in detecting intratumoral hemorrhage, aiding in diagnosis and management planning.
  • Further research may elucidate the specific risk factors and clinical implications of hemorrhage in different pituitary tumor subtypes.