Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

MRI in cerebellar hypoplasia

N deSouza1, R Chaudhuri, J Bingham

  • 1Department of Magnetic Resonance, Guys' Hospital, London, UK.

Neuroradiology
|January 1, 1994
PubMed
Summary

Cerebellar hypoplasia presents with diverse neurological symptoms, from severe neonatal issues to mild adult cases. MRI imaging is crucial for diagnosing cerebellar hypoplasia and associated brain abnormalities.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unequal allocation in randomised phase II trials.

Contemporary clinical trials·2025
Same author

Annexin A2 Contributes to Release of Extracellular Vimentin in Response to Inflammation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2025
Same author

Analysis insights to support the use of wastewater and environmental surveillance data for infectious diseases and pandemic preparedness.

Epidemics·2025
Same author

Patient centered guidelines for the laboratory diagnosis of Gaucher disease type 1.

Orphanet journal of rare diseases·2022
Same author

Imaging of lymphatic dysplasia in Noonan syndrome: Case studies and historical atlas.

Lymphology·2021
Same author

Neuronal inclusions resembling Negri bodies in the thalamus of a red kangaroo (Macropus rufus).

Australian veterinary journal·2021

Area of Science:

  • Neurology
  • Radiology
  • Medical Genetics

Background:

  • Cerebellar hypoplasia encompasses a spectrum of neurological conditions.
  • Presentation varies significantly, from neonatal mortality to asymptomatic adult findings.

Observation:

  • Magnetic Resonance Imaging (MRI) is essential for evaluating cerebellar size and abnormalities.
  • Seven cases of cerebellar hypoplasia with diverse etiologies were analyzed.
  • Associated anomalies included Chiari malformation, brain stem hypoplasia, Dandy-Walker cyst, pachygyria, and spinal dysraphism.

Findings:

  • MRI effectively identifies cerebellar hypoplasia and co-occurring structural brain abnormalities.
  • Diverse etiologies, including inherited disorders, spinal dysraphism, Joubert syndrome, and pontine agenesis, were observed.
  • Specific associated conditions like Chiari malformation and pachygyria were clearly visualized.

Implications:

  • Accurate imaging documentation aids in precise diagnosis of cerebellar hypoplasia.
  • Understanding associated anomalies is critical for comprehensive patient management.
  • Detailed imaging findings facilitate informed genetic counseling for affected families.

Related Experiment Videos