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[Simultaneous occurrence of lupus anticoagulant and acquired "storage pool" disease of thrombocytes]

P Soltész1, M Zeher, L Muszbek

  • 1Debreceni Orvostudományi Egyetem III. sz. Belgyógyászati Klinika.

Orvosi Hetilap
|May 8, 1994
PubMed

The authors describe the case of a female patient with a history of simultaneous abortion and deep vein thrombosis as well as moderate bleeding disturbances. Investigations revealed the presence of lupus anticoagulant while a thrombocyte "storage pool" disease was confirmed. This case demonstrates the association of these two haemostatic disturbances, and points to a possible relationship between them. Since detailed analyses failed to demonstrate the presence of antiplatelet antibodies, the authors suggest a possible damaging effect of lupus anticoagulant to the endothelium leading to thrombocyte activation.

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