Xenogeneic implants in primates. Collagen and chondroitin sulfate

This study was undertaken to examine histologically, in monkeys, the sequential healing phenomena of created two-walled osseous defects, which have been corrected by purified collagen and a mixed isomer of chondroitin sulfate. Four adult rhesus monkeys were used as experimental models and provided 23 specimens, from 0 to 56 days postoperatively. Sixteen of these served as implant specimens, and seven served as control specimens in which defects were corrected by curettage only. Two types of implant materials were utilized. The implants were compatible with osteogenesis. The two implant materials themselves did not differ in the healing events.