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Updated: Aug 19, 2026

12:03
Fertility Preservation in Patients with Severe Ovarian Dysfunction
Published on: March 25, 2021
A case of isolated TSH deficiency presenting as infertility
1Department of Endocrinology, Cobbold Laboratories, Middlesex Hospital, London, UK.
Postgraduate Medical Journal
|March 1, 1994
Abstract:
We report a case of late-onset isolated thyroid stimulating hormone deficiency in a woman who presented with oligomenorrhoea and secondary hyperprolactinaemia. Hypothalamic and pituitary radiology and function was otherwise normal. The underlying aetiology of this condition is thought to be due to an inborn defect in the thyrotroph and treatment is with standard thyroid replacement therapy.
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