[4 cases of Horton's temporal arteritis. Hypothesis on the possible correlations with rheumatic polymyalgia]
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An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
M C Ansaloni1, F Zizzi, M Giorgio
1Servizio di Pronto Soccorso e Medicina d'Urgenza, Ospedale Maggiore, USL 27, Bologna.
Abstract:
Giant cell arteritis (GCA) or temporal arteritis is an entity of unknown aetiology and uncertain autonomy for the close relationship with polymyalgia rheumatica (PMR). This work describes four patients with GCA alone. All patients had clinical and laboratoristic evidence of the disease and were treated with steroids. The distribution of HLA antigens showed an increased occurrence of DR4 and B8 antigens. Unfortunately, the small number of patients and the short period of observation don't allow to prove the exact nature of the link between GCA and PMR.
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