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Surgical management of esophageal cancer. A decade of change
J S Bolton1, J L Ochsner, A A Abdoh
1Department of Surgery, Ochsner Medical Institutions, Jefferson, Louisiana.
Objective:
To examine trends for use of transhiatal esophagectomy (THE) and to relate outcome variables to changes in use, controlling for preoperative risk.
Background:
High operative morbidity and mortality rates are reported with conventional transthoracic esophagectomy (TTE). Transhiatal esophagectomy has been proposed as an alternative but is controversial.
Methods:
In this retrospective study divided into early and late time periods, outcome variables were subjected to univariate and multivariate analyses.
Results:
Use of THE increased significantly in the late period (p < 0.0001). Patients who had THE had significantly higher American Society of Anesthesiologists (ASA) risk scores (p < 0.001). By the late period, 92% of patients with ASA III/IV scores were resected by THE. Postoperative morbidity decreased significantly and operative mortality decreased from 15% to 0% (p < 0.01) between the early and late time periods. By multivariate analysis, ASA > or = III and TTE were associated with adverse surgical outcome. Pathologic stage determined disease-free survival, which was 37% at 3 years for all survivors.
Conclusions:
Increased use of THE results in better operative outcome and does not adversely affect disease-free survival.