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Related Experiment Videos

Global overview of Lamisil

A Y Finlay1

  • 1Department of Dermatology, University of Wales College of Medicine, Cardiff, U.K.

The British Journal of Dermatology
|April 1, 1994
PubMed
Summary

Terbinafine (Lamisil) is an effective antifungal medication that reaches key skin and nail sites. This review details its efficacy for various fungal infections and discusses potential side effects.

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Area of Science:

  • Dermatology
  • Pharmacology
  • Mycology

Background:

  • Terbinafine (Lamisil) is a widely available antifungal medication.
  • Understanding its pharmacokinetic profile is crucial for effective treatment.
  • Fungal infections of the skin and nails remain a significant clinical challenge.

Purpose of the Study:

  • To review the clinical significance of terbinafine.
  • To evaluate the drug's penetration into the stratum corneum and nail plate.
  • To summarize evidence of terbinafine's efficacy in treating fungal diseases and discuss its safety profile.

Main Methods:

  • Literature review of terbinafine's properties and clinical applications.
  • Analysis of pharmacokinetic data regarding drug distribution to target tissues.
  • Compilation of clinical trial data and case reports on terbinafine's efficacy and safety.

Main Results:

  • Terbinafine demonstrates favorable distribution to the stratum corneum and nail plate.
  • Evidence supports terbinafine's value in treating various dermatophyte infections.
  • The drug's efficacy is balanced against a discussion of its potential side effects.

Conclusions:

  • Terbinafine is a valuable antifungal agent with good penetration to target sites.
  • Its effectiveness in treating specific fungal conditions is supported by clinical evidence.
  • A comprehensive understanding of its side effect profile is essential for safe and effective use.

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