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Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
Out-patient medical care in Edinburgh for IDU-related HIV
R P Brettle1, L Willocks, B A Hamilton
1Regional Infectious Disease Unit, City Hospital, Edinburgh, UK.
Insights
Combined medical and drug clinics successfully provided healthcare to HIV-infected individuals, reducing injection drug use (IDU). However, appointment default rates increased, particularly among those not attending all-day clinics.
Area of Science:
- Public Health
- Infectious Diseases
- Addiction Medicine
Background:
- The study addresses the challenge of providing consistent healthcare to individuals with Human Immunodeficiency Virus (HIV), many of whom are injection drug users (IDUs).
- Previous efforts showed success in reducing missed appointments with methadone treatment and all-day clinics.
- A recent increase in appointment default rates necessitates further investigation into contributing factors.
Purpose of the Study:
- To evaluate the effectiveness of combined medical and drug clinics in managing HIV-infected injection drug users.
- To analyze appointment default rates and identify factors associated with missed appointments.
- To assess changes in injection drug use and opiate use among HIV-positive and HIV-negative patients.
Main Methods:
- Retrospective analysis of patient data from combined medical and drug clinics between 1986 and 1990.
- Tracking of appointment attendance, default rates, and patient loss to follow-up.
- Self-reported data collection on injection drug use and opiate use.
Main Results:
- While laboratory monitoring (92-95%) and low loss to follow-up (14% cumulative over 5 years) were maintained, appointment default rates rose from 17% to 25% between 1989 and 1990.
- Increased default rates were significantly associated with not attending the all-day clinic.
- HIV-positive individuals showed a significant reduction in self-reported injection drug use, while non-HIV-infected patients reported increased opiate use.
Conclusions:
- Combined medical and drug clinics, with a multidisciplinary approach, are effective in delivering healthcare to HIV-infected IDUs.
- Strategies to address appointment default, particularly for those not attending all-day clinics, are needed.
- The observed reduction in IDU among HIV-positive patients is a positive outcome, but ongoing monitoring of opiate use in the non-HIV-infected group is warranted.
Abstract:
Using combined medical and drug clinics, by the end of 1990 we had initiated contact with 511 HIV positive individuals, 75% injection drug use (IDU) related. We have previously reported a significant reduction in the number of missed appointments from 1985-89 following the introduction of methadone and an all day clinic, but between 1989 and 1990 the appointment default rate rose from 17 to 25%. A significant percentage increase in missed appointments was, however, only seen in those not attending the all day clinic (chi 2(3) = 121.3, p < 0.001). An analysis of the patients missing appointments during 1989-90 revealed that 36-45% of patients attending each year missed only 1 or 2 appointments, that the majority of missed appointments each year were accounted for by less than 20% of the patients, around 60% of these patients missed appointments in both years and that only 2% of patients attending both years consistently miss 3 or more appointments per year. Laboratory monitoring of HIV, that is at least one sampling episode in a year, was achieved, however, in 92-95% of the patients attending each year. The annual number of patients lost to follow-up varied between 7 and 11% per year, but did not change significantly over time, whilst the cumulative number of HIV infected individuals lost to follow-up after 5 years was only 14%. Between 1986 and 1990 self-reported reduction in IDU was more likely in HIV positive than negative individuals; the number of HIV positive individuals who reported injecting for more than 50% of the year fell from 40 to 5% (chi 2(4) = 15.23, p < 0.01) whilst the number who reported at least one injection per year fell from 51 to 23% (chi 2(4) = 62.06, p < 0.001). By comparison amongst non-HIV-infected patients the percentage who reported opiate use for more than 50% of the visits during a year rose from 54% in 1986 to a peak of 70% in 1989 (chi 2(4) = 10.22, p < 0.05) and those who reported opiate use at least once during the year rose from 57% in 1986 to a peak of 75% in 1989 (chi 2(4) = 14.3, p = 0.006). Combined medical and drug clinics from 1986 to 1990 together with a multi-disciplinary team approach to medical care was successful in delivering health care to HIV-infected injection drug users.(ABSTRACT TRUNCATED AT 400 WORDS)
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