Related Experiment Videos
Precise mapping of the EGF receptor gene on the human chromosome 7p12 using an improved fish technique
Y Wang1, S Minoshima, N Shimizu
1Department of Molecular Biology, Keio University School of Medicine, Tokyo, Japan.
The Japanese Journal of Human Genetics
|December 1, 1993
Abstract:
The gene for epidermal growth factor receptor (EGFR) has been localized to the p14-p12 region of human chromosome 7 by somatic cell hybridization and radioisotope in situ hybridization techniques. In this paper, we report the precise mapping of the EGFR gene to the band p12 of chromosome 7 using a novel method in which fluorescence images from in situ hybridization and Q-banding are computer graphically merged. The novel procedure is described in detail.