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Investigating Mast Cell Secretory Granules; from Biosynthesis to Exocytosis
Published on: January 26, 2015
Electron microscopic localization of silver binding proteins in the cytoplasmic granules of guinea pig eosinophil
1Cantacuzino Institute, Bucharest, Romania.
Roumanian Archives of Microbiology and Immunology
|April 1, 1993
Abstract:
A new electron optic configuration is described in the specific granules of eosinophil leukocytes. Application of the ammonium silver nitrate impregnation after treatment of intact cells with formaldehyde-OsO4 solution reveals regular deposits of 50 A-electron-opaque particles which are localized in the axial region of the central core. They contain acid-extractable proteins that seem to include the eosinophil basic proteins which participate to the local immune response of the host.

