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Malignant lymphoma and dermatitis herpetiformis
S K Bose1, J P Lacour, I Bodokh
1Department of Dermatology, Hôpital Pasteur, University of Nice, France.
Abstract:
We report 2 cases of dermatitis herpetiformis (DH) with lymphoma: a non-Hodgkin's malignant histiocytic lymphoma and a rare phenotype of Hodgkin's disease. With these 2 cases, 32 cases of DH complicated by lymphoma have now been documented. Reviewing the literature we show that the majority of lymphomas (78.1%) arises from the gastro-intestinal tract and that almost all cases of DH with lymphoma are associated with coeliac disease. The possible preventive role of a gluten-free diet is discussed.