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Early malignant histiocytosis of the intestine: an autopsy report
K Ohshima1, K Yoshitake, H Ugaeri
1First Department of Pathology, School of Medicine, Fukuoka University, Japan.
Virchows Archiv : an International Journal of Pathology
|January 1, 1994
Abstract:
A 63-year-old man with malignant histiocytosis of the intestine died 3 days after gastrectomy for early gastric adenocarcinoma. Malignant histiocytosis of the intestine was unexpectedly found at autopsy. The intestine was thickened with mucosal erosions. Histologically, a few atypical large histiocyte-like cells were found in focal aggregates in the mucosa. These large cells expressed the T-cell antigen and monoclonality was demonstrated by the polymerase chain reaction showing variable-joining segment rearrangement in the T-cell receptor delta-chain gene. Malignant histiocytosis of the intestine was thus diagnosed.