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Related Experiment Videos

Citrobacter meningitis in adults

L M Tang1, S T Chen, T N Lui

  • 1Department of Neurology, Chang Gung Memorial Hospital and Chang Gung Medical College, Taipei, Taiwan.

Clinical Neurology and Neurosurgery
|February 1, 1994
PubMed
Summary
This summary is machine-generated.

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Citrobacter meningitis, rare in adults, can be caused by gram-negative bacilli. This study highlights rare adult cases of Citrobacter diversus and Citrobacter freundii meningitis, emphasizing potential risks in specific patient groups.

Area of Science:

  • Infectious Diseases
  • Neurology
  • Microbiology

Background:

  • Citrobacter meningitis is typically observed in neonates and young children.
  • Adult cases of Citrobacter meningitis are exceptionally rare in medical literature.

Observation:

  • This report details two adult patients diagnosed with Citrobacter meningitis.
  • A 46-year-old male presented with mixed bacterial meningitis involving Citrobacter diversus and Klebsiella oxytoca.
  • A 64-year-old female was diagnosed with Citrobacter freundii meningitis.

Findings:

  • A literature review identified only four previously reported adult cases of Citrobacter diversus or Citrobacter freundii meningitis.
  • Predisposing factors in adult patients included facial fractures, neurosurgery, alcoholism, and diabetes mellitus.

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  • Antibiotic therapy was effective in four out of five reported adult cases with known outcomes.

    • Implications:

    • This study underscores that various gram-negative bacilli can cause severe central nervous system infections in adults under specific circumstances.
    • Clinicians should consider Citrobacter species in the differential diagnosis of meningitis in adult patients with relevant predisposing conditions.