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[Endobronchial mass caused by tuberculosis]

J Laufer1, A Szeinberg, A Augarten

  • 1Pediatric Dept. B., Chaim Sheba Medical Center, Tel Hashomer.

Harefuah
|March 1, 1994
PubMed
Summary
This summary is machine-generated.

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Tuberculosis can present as an endobronchial mass in children, even with an initial negative tuberculin test. Prednisone therapy may alter tuberculin test results, highlighting the importance of considering tuberculosis in pediatric differential diagnoses.

Area of Science:

  • Pediatric Pulmonology
  • Infectious Diseases
  • Pediatric Radiology

Background:

  • A 2-year-old girl presented with cough and was treated for presumed small airway obstruction.
  • Initial treatment included prednisone and bronchodilators.
  • Diagnostic imaging revealed signs of airway obstruction.

Observation:

  • Fluoroscopy showed right lung hyperinflation and mediastinal shift during expiration.
  • Bronchoscopy identified an endobronchial mass.
  • An initial tuberculin test was negative.

Findings:

  • Histopathological examination of an enlarged mediastinal lymph node suggested tuberculosis.
  • A repeat tuberculin test after prednisone therapy became positive.
  • Prednisone likely altered the initial tuberculin skin test reactivity.

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Implications:

  • Tuberculosis should be considered in the differential diagnosis of endobronchial masses in children.
  • The diagnostic approach for pediatric endobronchial lesions requires careful consideration of infectious etiologies.
  • Immunosuppressive therapy can affect the interpretation of tuberculin skin tests.