Malignant angioendotheliomatosis with retinal detachments in a dog

A Golden Retriever with bilateral conjunctival hyperemia, chemosis, and blepharospasm was determined to have malignant angioendotheliomatosis, which is an uncommon neoplastic disorder of dogs and human beings. It was believed to be of endothelial origin, but evidence in human beings indicates a lymphoid origin. The histogenesis of the disease in the dog was confirmed to be of lymphoid origin by use of a canine lymphoma-specific immunoperoxidase assay. The prognosis for malignant angioendotheliomatosis in dogs is poor, but with early diagnosis, the condition is potentially manageable.