[Experimental studies on the usefulness of photodynamic method in diagnosis and treatment of melanoma]

The authors present results of experimental studies on the usefulness of hematoporphyrin and laser in diagnosis and treatment of intraocular tumors. An amelanotic Greene melanoma was implanted into anterior chamber of 10 rabbits. After administration of HpD the tumor was irradiated with laser light of wavelengths 406 nm for diagnosis and 630 nm for selective destruction of neoplastic cells. During follow-up the tumor was growing pale and its gradual shrinkage was observed. In histopathological examination multiple area of necrosis with total destruction of blood vessels were found.