A new questionnaire for gastroesophageal reflux disease
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Updated: Nov 9, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
G R Locke1, N J Talley, A L Weaver
1Division of Gastroenterology and Internal Medicine, Mayo Clinic Rochester, Minnesota 55905.
Objective:
To develop a questionnaire to measure gastroesophageal reflux disease in the community and to test its reliability and validity.
Material And Methods:
The reliability of the questionnaire was measured by a test-retest procedure in 38 outpatients and 77 community residents 25 to 74 years of age, whereas concurrent validity was evaluated by comparing findings from a physician interview with self-report data from 51 patients. For statistical analysis of the reliability of each question, the kappa statistic and the 95% confidence interval were calculated.
Results:
The questionnaire was easy to understand and well accepted. The reliability (median kappa for outpatients, 0.70 [interquartile range, 0.59 to 0.81]; median kappa for population sample, 0.70 [interquartile range, 0.60 to 0.81]) and validity (median kappa, 0.62 [interquartile range, 0.49 to 0.74]) were acceptable.
Conclusion:
Our initial results suggest that this questionnaire is valid and should be applicable in population-based studies to assess gastroesophageal reflux disease.
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