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Related Experiment Videos

Cutaneous laser Doppler flowmetry: applications and findings

A M Schabauer1, T W Rooke

  • 1Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic Rochester 55905.

Mayo Clinic Proceedings
|June 1, 1994
PubMed
Summary

Laser Doppler flowmetry (LDF) is a non-invasive tool for assessing microcirculatory blood flow. Despite early challenges, LDF has evolved into a technically acceptable method for evaluating skin circulation.

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Area of Science:

  • Biomedical Engineering
  • Medical Physics

Background:

  • Laser Doppler flowmetry (LDF) is a technique used to measure microcirculatory blood flow.
  • It non-invasively assesses blood flow by analyzing Doppler-shifted laser light.
  • The technology has evolved significantly since its inception.

Purpose of the Study:

  • To review the historical development of LDF.
  • To analyze the strengths, weaknesses, and applications of LDF.
  • To explore current and future uses of LDF in various medical fields.

Main Methods:

  • Literature review and summary of published studies on LDF.
  • Focus on cutaneous and microcirculatory applications.
  • Inclusion of noncutaneous and nonvascular applications.

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Main Results:

  • LDF has shown considerable potential for evaluating cutaneous circulation.
  • Early challenges in sampling, stability, and reproducibility have been addressed through technical refinements.
  • The technique is now considered technically acceptable.

Conclusions:

  • LDF is valuable for assessing microcirculation and real-time skin blood flow.
  • Successful applications include studies on vascular disorders, neuropathies, tumors, ulcers, and post-surgical patients.
  • LDF offers a non-invasive and inexpensive method for blood flow assessment.