[Dynamics of the Paul Bunnel-Davidsohn test during infectious mononucleosis]

The study was aimed at establishment whether dependence exists between severity of clinical course of infectious mononucleosis and the level of heterophilic antibodies in the PBD test. Antibody titers were measured three times during illness in 34 persons with infectious mononucleosis, divided into two groups: I--patients with moderate course of the disease and II--patients with moderate-severe course. In five persons out of 34 tested negative PBD test result was obtained, although these patients exhibited symptoms on mononucleosis confirmed by other laboratory methods. Positive result of the PBD test was occurring more frequently and mean titer of heterophilic antibodies was higher in patients with moderate clinical course than in persons with moderate-serious course of the disease. Decrease of PBD test titer was observed between first and third determination in both groups of patients.