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Related Experiment Videos

[Pseudotuberculosis in simians]

R I Krylova, E K Dzhikidze, M N Machavariana

    Arkhiv Patologii
    |January 1, 1976
    PubMed
    Summary

    Pasteurella pseudotuberculosis caused intestinal disease in monkeys, leading to enterocolitis, enlarged spleens, and liver necroses. This study details the pathological findings of pseudotuberculosis in non-human primates.

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    Area of Science:

    • Veterinary Pathology
    • Primate Medicine
    • Infectious Diseases

    Context:

    • The study examines the pathological-anatomic features of Pasteurella pseudotuberculosis infection in red monkeys and green marmosets.
    • Pseudotuberculosis is a bacterial infection that can affect various animal species.

    Purpose:

    • To describe the pathologo-anatomic manifestations of Pasteurella pseudotuberculosis in non-human primates.
    • To document the gross and microscopic lesions associated with this infection.

    Summary:

    • The majority of infected monkeys presented with an intestinal form of pseudotuberculosis.
    • Key findings included severe ulcerative enterocolitis, splenomegaly with hepatic and splenic necroses, mesenteric lymphadenopathy with macrophagal reactions, circulatory disturbances, hemorrhages, and microbial colonies within tissues.
    • Pasteurella pseudotuberculosis was successfully isolated from deceased animals, confirming the causative agent.

    Impact:

    • Provides detailed pathological data on pseudotuberculosis in primates, aiding in diagnosis and understanding disease progression.
    • Highlights the significant gastrointestinal and systemic effects of Pasteurella pseudotuberculosis infection in these species.
    • Contributes to the knowledge base for managing and preventing infectious diseases in captive and wild primate populations.

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