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Imaging of gallbladder carcinoma

S A Rooholamini1, N S Tehrani, M K Razavi

  • 1Department of Radiological Sciences, Olive View--UCLA Medical Center, Sylmar 91342.

Radiographics : a Review Publication of the Radiological Society of North America, Inc
|March 1, 1994
PubMed
Summary

Gallbladder carcinoma, the most common biliary tract malignancy, presents with varied clinical and radiologic findings. Understanding these features improves preoperative diagnosis of this rare cancer.

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Area of Science:

  • Oncology
  • Radiology
  • Gastroenterology

Background:

  • Gallbladder carcinoma is the most common malignancy of the biliary tract, despite its low overall prevalence.
  • Early diagnosis is crucial for improving patient outcomes.

Purpose of the Study:

  • To review the clinical, radiologic, and histologic features of gallbladder carcinoma.
  • To enhance the preoperative diagnostic accuracy of gallbladder carcinoma.

Main Methods:

  • Retrospective review of 59 histologically confirmed cases of gallbladder carcinoma.
  • Analysis of clinical manifestations, radiologic findings, and histologic diagnoses.

Main Results:

  • Common clinical signs include right upper quadrant pain, anorexia, weight loss, and jaundice.

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  • Radiologic findings frequently show gallbladder wall thickening (49%), a mass in the gallbladder fossa (37%), and associated cholelithiasis (64%).
  • Adenocarcinoma (90%) was the predominant histologic type, followed by squamous cell carcinoma (10%).

    • Conclusions:

    • Gallbladder carcinoma exhibits diverse clinical and radiologic features.
    • Awareness of these radiologic characteristics is key to improving preoperative diagnosis.
    • Differential diagnosis should consider conditions causing gallbladder wall thickening.