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Salmonella typhi meningitis

H Lecour1, L Santos, M Oliveira

  • 1Department of Infectious Diseases, School of Medicine, Hospital S. João, Porto, Portugal.

Insights

Typhoid fever rarely causes meningitis, but this case highlights a Salmonella typhi infection in the meninges of a 70-year-old woman. Treatment with ampicillin resulted in hearing loss.

Area of Science:

  • Infectious Diseases
  • Neurology
  • Microbiology

Background:

  • Typhoid fever, caused by Salmonella enterica serovar Typhi (Salmonella typhi), remains endemic in many regions.
  • Meningeal involvement, or meningitis, is an infrequent complication of typhoid fever.

Observation:

  • A case study of a 70-year-old woman presenting with Salmonella typhi meningitis is detailed.
  • The patient's clinical presentation and diagnostic findings are described.

Findings:

  • The patient was successfully treated with ampicillin for Salmonella typhi meningitis.
  • The primary sequela observed post-treatment was unilateral (right-sided) deafness.

Implications:

  • This case underscores the importance of considering Salmonella typhi meningitis in endemic areas, even with rare presentations.
  • Early diagnosis and appropriate antibiotic therapy are crucial for managing this severe complication.
  • The occurrence of deafness highlights the potential for neurological sequelae and the need for monitoring auditory function.

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