Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Height, lung function, and mortality from cardiovascular disease among the elderly

N R Cook1, P R Hebert, S Satterfield

  • 1Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215.

American Journal of Epidemiology
|June 1, 1994
PubMed
Summary

In elderly women, shorter height is linked to increased cardiovascular disease death risk, independent of lung function. This association suggests height is a significant factor in cardiovascular health outcomes for older women.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A prospective study of blood pressure and risk of cataract in men.

Annals of epidemiology·2001
Same author

G20210A mutation in the prothrombin gene and the risk of recurrent venous thromboembolism.

Journal of the American College of Cardiology·2001
Same author

Relations of body fat distribution and height with cataract in men.

The American journal of clinical nutrition·2000
Same author

Systolic and diastolic blood pressure, pulse pressure, and mean arterial pressure as predictors of cardiovascular disease risk in Men.

Hypertension (Dallas, Tex. : 1979)·2000
Same author

An overview of the 4 randomized trials of aspirin therapy in the primary prevention of vascular disease.

Archives of internal medicine·2000
Same author

Clinical and research challenges in risk factors for cardiovascular diseases.

European heart journal·2000

Area of Science:

  • Gerontology
  • Cardiovascular Epidemiology
  • Biometrics

Background:

  • Cardiovascular disease remains a leading cause of mortality in older adults.
  • Previous research has explored various risk factors for cardiovascular disease, but the role of body stature is less understood.
  • Understanding modifiable and non-modifiable risk factors is crucial for public health interventions.

Purpose of the Study:

  • To investigate the association between self-reported height and cardiovascular disease mortality in an elderly cohort.
  • To determine if this association is mediated by lung function, such as peak expiratory flow rate (PEFR).
  • To examine potential sex differences in the height-cardiovascular disease mortality relationship.

Main Methods:

  • A cohort study of 3,809 individuals aged 65+ in East Boston, Massachusetts, surveyed in 1982-1983.

Related Experiment Videos

  • Data collected included self-reported height and weight, and measured peak expiratory flow rate (PEFR).
  • Vital status and cause of death were tracked through 1988, with statistical adjustments for age, BMI, and smoking.

    • Main Results:

    • In women, a statistically significant trend showed decreased cardiovascular death risk with increasing height quintiles (p=0.015), with the tallest quintile as reference.
    • In men, the association between height and cardiovascular death was not statistically significant.
    • A curvilinear relationship between height and cardiovascular death was observed in both sexes.
    • Height remained a significant predictor of cardiovascular death in women even after adjusting for PEFR and other risk factors.

    Conclusions:

    • Height is associated with cardiovascular disease mortality in elderly women, independent of lung function.
    • The findings suggest that body stature may be an intrinsic risk factor for cardiovascular events in older women.
    • Further research is warranted to elucidate the biological mechanisms underlying this observed relationship.