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[A 50-year-old man with metamorphopsia and optic nerve swelling]
Y Nakajima1, T Kitada, Y Mizutani
1Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
No to Shinkei = Brain and Nerve
|May 1, 1993
Summary
This case study describes a patient with metamorphopsia and papilledema, ultimately diagnosed with leptomeningeal carcinomatosis. Despite initial treatment, the patient experienced neurological decline and expired.
Area of Science:
- Neuro-oncology
- Ophthalmology
Background:
- Leptomeningeal carcinomatosis (LC) is a rare complication of cancer.
- Early diagnosis and treatment are crucial for improving patient outcomes.
Observation:
- A 50-year-old male presented with metamorphopsia, headache, and papilledema.
- Cerebrospinal fluid (CSF) analysis revealed atypical cells, and imaging showed optic nerve swelling.
Findings:
- The patient was treated with chemotherapy and intrathecal agents, showing initial improvement.
- Recurrence of symptoms, including gait disturbance and neurological decline, led to a fatal outcome.
Implications:
- This case highlights the challenges in diagnosing and managing leptomeningeal carcinomatosis.
- Metamorphopsia and papilledema can be early signs of leptomeningeal disease.