Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypothyroidism: does treatment cure dementia?

R M Clarnette1, C J Patterson

  • 1Department of Geriatric Medicine and Extended Care, Osborne Park Hospital, Western Australia.

Journal of Geriatric Psychiatry and Neurology
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Effect of Multiple Assessments on Delirium Detection: a Pilot Study.

Canadian geriatrics journal : CGJ·2020
Same author

Bias in beliefs about the self is associated with depressive but not anxious mood.

Comprehensive psychiatry·2017
Same author

The Community Assessment of Risk Instrument: Investigation of Inter-Rater Reliability of an Instrument Measuring Risk of Adverse Outcomes.

The Journal of frailty & aging·2016
Same author

The WHIM-like CXCR4(S338X) somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom's Macroglobulinemia.

Leukemia·2014
Same author

Detection of MYD88 L265P in peripheral blood of patients with Waldenström's Macroglobulinemia and IgM monoclonal gammopathy of undetermined significance.

Leukemia·2014
Same author

Severe hypoglycaemia and cognitive impairment in older patients with diabetes: the Fremantle Diabetes Study.

Diabetologia·2009

Investigating dementia causes, this study found hypothyroidism rarely leads to reversible dementia. More research, like a randomized controlled trial, is needed to confirm if treating thyroid issues improves cognitive function in dementia patients.

Area of Science:

  • Neurology
  • Endocrinology

Background:

  • Dementia evaluation traditionally includes searching for reversible causes.
  • Hypothyroidism is often considered a potentially reversible cause of cognitive decline.

Purpose of the Study:

  • To assess the available evidence supporting hypothyroidism as a reversible cause of dementia.
  • To determine the frequency of hypothyroidism-induced reversible dementia in existing literature.

Main Methods:

  • A comprehensive literature search was conducted to identify studies on dementia etiology.
  • Analysis focused on cases where dementia might be reversible due to hypothyroidism.
  • 2781 cases from etiological studies of dementia were reviewed.

Main Results:

Related Experiment Videos

  • Only one case of reversible dementia attributed to hypothyroidism was found among 2781 analyzed cases.
  • Previous reports on this topic may suffer from diagnostic and follow-up limitations.

    • Conclusions:

    • The evidence suggests hypothyroidism is a very rare cause of reversible dementia.
    • Further investigation, specifically a randomized controlled trial, is required to definitively establish the link between hypothyroidism treatment and cognitive improvement in dementia.