Related Experiment Videos
Identification and localization of G(i) alpha 3 in the clonal adipocyte cell lines HGFu and Ob17
M Cadrin1, N McFarlane-Anderson, N Bégin-Heick
1Department of Pathology, University of Ottawa, ON, Canada.
Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire
|November 1, 1993
Abstract:
The HGFu and Ob17 cell lines, derived from adipose tissue of lean (+/?) and ob/ob mice, respectively, express several G-protein peptides. Investigation of the expression and subcellular localization of the G(i) alpha 3 subunit showed that this peptide is associated with the Golgi apparatus. These findings indicate a role for this subunit in vesicular traffic and are in agreement with the view of the adipocyte as a secretory cell.