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[Quantitative immunohistochemical study of ras oncogene product P21 in laryngeal carcinomas and its clinical

Z S Liu1

  • 1Xijing Hospital of 4th Military Medical University, Xi'an.

Zhonghua Er Bi Yan Hou Ke Za Zhi
|January 1, 1993
PubMed

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The Ras Gene02:38

The Ras Gene

The Ras-gene-encoded proteins are regulators of signaling pathways controlling cell proliferation, differentiation, or cell survival. The Ras-gene family in humans constitutes three primary members—the HRas, NRas, and KRas. These genes code for four functionally distinct yet closely related proteins—the HRas, NRas, KRas4A, and KRas4B. The involvement of mutant Ras genes in human cancer was first discovered in 1982 and is among the most common causes of human tumorigenesis.
Ras is a superfamily...