Related Experiment Videos
Effect of thyroxine on DNA methyltransferase activity in cerebellum of rat
Biochemistry and Molecular Biology International
|December 1, 1993
Abstract:
DNA methyltransferase activity increased significantly in cerebellum from day 4 to day 8 and decreased in 30 day old rats. It was maintained at lower levels in the adult rats. Thyroxine administration markedly stimulated DNA methyl- transferase activity in the newly born pups. However, it did not cause any effect on this enzyme activity in 8 day old rat cerebellum. These results show that thyroxine has a role in the regulation of DNA methyltransferase activity in cerebellum of rat during early stages of development.